When should a MONA LISA® IUD be inserted?

MONA LISA® IUD can be safely inserted any time during the menstrual cycle, although some physicians recommend insertion during menstruation as it minimizes the risk of non-diagnosed pregnancy.

Insertion should be delayed until 6 weeks after delivery, and 12 weeks after a caesarean section. Insertion any time sooner results in risks of perforation or expulsion of the MONA LISA® IUD.

There are no associated risks with having a MONA LISA® IUD inserted while breastfeeding.

Healthcare providers’ frequently asked questions

What are the risks associated with MONA LISA® IUDs?

  • In rare cases certain women, in particular women who have never given birth, are more susceptible to fainting, a slowing of their pulse, and other neurovascular episodes during and immediately after insertion or removal of a MONA LISA® IUD.
  • Perforation: In rare cases, a MONA LISA® IUD can penetrate the wall of the uterus during insertion. This rare complication occurs at a rate of 0.7 to 1.6 per 1000 insertions. If perforation occurs, the MONA LISA® IUD should be removed immediately.
  • Expulsion: A MONA LISA® IUD may partially or completely fall out of the uterus. Expulsion of any intrauterine device is most common in the first year of use. The expulsion rates are often higher in women who have never been pregnant, in women who have the MONA LISA® IUD inserted immediately after giving birth and in women who have had a previous expulsion of an intrauterine device.


  • If there is a pregnancy or a suspected pregnancy
  • If there is a past history of ectopic pregnancy or predisposing factors
  • In case of an abnormally shaped uterus
  • If there is a sexually transmitted disease
  • If there is pelvic inflammatory disease (PID)
  • If there is an infection of the uterus after a pregnancy or abortion in the last 3 months
  • If there is a cancer of the uterus or cervix
  • If there is unexplained vaginal bleeding
  • If there is an infection in the cervix
  • If the patient has Wilson’s disease
  • If the patient is allergic to copper


Published reports have indicated diminished efficacy in the presence of long term use of non-steroidal anti-inflammatory drugs (especially acetyl salicylic acid) and of corticoids. Short term use in the treatment of dysmenorrhoea with non-steroidal anti-inflammatory drugs does not appear to reduce contraceptive efficacy.5,6,7,8


Do not perform diathermy (short wave or microwave) of the sacral or abdominal region since heating of the copper can damage the IUD and may cause heat injury to the surrounding tissue.5,6,7,8


  1. Society of Obstetricians and Gynaecologists of Canada (SOGC). Canadian Contraceptive Consensus (parts 1 to 4). J Obstet Gynaecol Can 2015:37(10)S1-S28,182-199.
  2. K.H. Kurtz, P.A. Meier-Oekhlke. The CU Safe 300 IUD, a new concept in intrauterine contraceptions: first-year results of a large study with a follow-up of 1017 acceptors. Advances in Contraception 1991:7:291-300
  3. United Nations Development Programme/United Nations Population Fund/ World Health Organization/ World Bank, Special Programme Research, Development and Research Training in Human Reproduction. Long-Term Reversible Contraception Twelve Years of Experience with the TCu380A and TCu220C. Contraception 1997:56:341-352
  4. S Wu et al. Copper T380A intrauterine device for emergency contraception: a prospective, multicentre, cohort clinical trial. BJOG An International Journal of Obstetrics and Gynaecology 2010:17:1205–1210
  5. MONA LISA® 10 (CuT 380A QL). Physician ML10. 2015-July:1-3. Available
    Accessed on June 15, 2017
  6. MONA LISA® 5 Standard (NT Cu380). Physician ML5. 2015-July:1-3. Available
    Accessed on June 15. 2017
  7. MONA LISA® 5 Mini (NT Cu 380 Mini). Physician ML5. 2015-July:1-3. Available
    Accessed on June 15, 2017
  8. MONA LISA® N (ST Cu 300). Physician MLN. 2015-July:1-3. Available
    Accessed on June 15, 2017